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Monday, October 12, 2009

Why doesn't adult medicine need a dosage chart like children's medicine?

Adults are different in weight and size as well... so why is it ok for an adult who is 110 pounds to take the same two tylenol as an adult who is 220 pounds? Does tylenol or any other drug company feel that the medication will work the same on both. ... Just wondering since I took some medication for a cold.
Answer:
For the most part, all the above answers are correct. Children have a lesser ability to metabolize, biotransfer and excrete medications that health adults. Their liver and kidneys (primary sites of biotransformation and excretion) are not as well developed in children as in a healthy adult. Another factor that figures into it is the difference in body fat and protein between children and adults. Some medications are lipid (fat) bound and some are protein bound. Hence, all of these factors are taken into consideration in pediatric dosages. However, many medications, prescription - not usually over the counter, are also weight based in adults for the same reasons. A final thought 鈥?geriatric medication dosages are also more critical with respect to dosages because of a decline in liver and renal functions.
I think it's because children metabolize things differently. Guaffasein is a mucus thinner in adult medicines, but it doesn't work with infants. Some decongestants make kids hyper, whereas...they wouldn't affect an adult. Their systems are just more sensitive to different chemicals and chemical combinations than adults. As to adults.I think once you hit a certain weight, a double dose won't do any more than the largest dose on the package. I think they list the adult dose pretty much at the limit of what the product can do.
Children are more easily overdosed to bad effect. And in reality there are dosing charts for height and weight for adults its just that its easier to market one size fits all..and a slight over or under dose in an adult is easier for the adult body to handle.
in adults, they usually start a small dose, and increase or decrease as it as needed (titrate it), unless it is and emergency, and they need an exact dose (they pull out the calculator) or it is sensitive medication that can easily kill (like IV potassium)

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